As mentioned again, this isn't something I can replicate and the single digit number of folks who have reported a similar issue get it resolved once they fixed their CPU affinity, memory usage, framelimiter, external apps limiting frames (isb, etc), AV, conflicting overlay causing focus problems, and especially the new UI engine (which coincidentally is a performance hog + framelimiter doesn't work on.
Without something more tangible to try and replicate, I'm going to have to go on the assumption that you have a background performance issue of some kind.
If you haven't already

ensured you don't have conflicting overlay running, I would do that.
Clicking might be giving you "I'm doing stuff here" power due to some conflict.