A whole lot easier with MQ2, if you're going to have a healer/enc combo and intend to charm etc. I'd suggest a druid/enc. Dru can snare the mob and port/heal/dps. The cleric won't be able to use some of its more useful heal abilities (div arb/epic) on enc pets at higher levels/later expansions.
Personally I'd go dru/enc, but I haven't done any of the TLP stuff and only have memories from 2003(LDoN) and onwards