which ui are you using? i hate default so i had pieced together a ui from eqinterface. things would randomly bug, not work, half the time my xtarget wouldn't show up etc. i made the swap to the full sparxx ui about a month ago and it's worked flawlessly ever since. you of course still need to copy over the ui pieces from MQ2, but once it's all in there and you setup your layout it's $$$$.
*Edit* also on Ragefire