I was doing it manually. You can 6 box Naggy + Vox. I was running 4 mages and 2 necros, necros could split pull, pets did the rest of the work. Just resummon pets, naggy and vox themselves don't bother with buffing them due to debuffs. Doing the missions themselves you can do it pretty easily with 2 w/ mage + necro. 3 add in an enchanter, past that add whatever. For raid fights, just gotta keep your casters out of AoE range, Vox may need to have 3 in at a time due to fear + leash. Naggy's room can be a major pain to split, but with practice it's not so bad.
I used isboxer more than mq2 though for it since I valued the key mirrors more. Basically had spells I wanted all in the same key locations, so I could for instance summon a pet with all 6 toons at once. mq2 was great for the awesome autofollow.