Which Macro are you trying to use? Is it even listed when you do the "listmacro" command in game? If it isn't, you must first copy and paste the macro into Notepad (or something similiar) and save it as a ".mac" file. Save it in the folder that contains the macros. My path to this folder (on my computer, yours may be different) is c:\MQ2\Release\macro. Once it is saved in the Macros folder, start MQ2, then start EQ. Once in game, do the listmacro command and see if it is listed. If it is, merly type /macro (whatevername).mac and it should start. An example would be.....
/mac RandFollow.mac
Randfollow is one of the macros that is included with MQ2 when you download the zip and complite it.
Hope this helps.