https://www.redguides.com/community/threads/24748-MQ2Cursor
turn the plugin on
have the offending item on your cursor and type in "/cursor 0" and it will auto destroy the item anytime it shows up on your cursor.
The plugin will not do anything so long as the item window, bank window, spellbook, or TS windows are open. So if you screw up the item, just open say the item window, so you can get the item on the cursor and redo the command properly.
I find this works well for me, especially if you use MQ2Melee to auto forage. And this way you are not trying to maintain 5-10-100 different loot lists.
The plugin maintains it's list with the same character file that MQ2Melee uses, and looks something like:
Rich (BB code):
[MQ2Cursor_ItemList]
1038=Tattered Cloth Sandal
12483=Radiant Meteorite|20
12563=Bookworm
12567=Fetid Fluid
12568=Deadly Mushroom
12574=Cockroach
12575=Dusty Cobwebs
12633=Lichenclover|20
12638=Sop Bark
12639=Mudcomb
12640=Drench Flower
12765=Giant Hornet Egg|1000
12767=Emerald Orange|20
12768=Emerald Palm Root
12771=Flarefire Seeds
12775=Frontier Stink Beetles
12776=Gold Nugget
12777=Gold Nugget
12787=Cockatrice Egg|1000
incase you prefer hand typing it. Nothing behind it is auto destroy, and "|####" saves up to that number, and then destroys the items after that limit.
This will NOT prevent a macro from occasionally being faster then the plugin and auto inventorying an item though (so it is not fool proof) but it does work well for the most part.
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You may want to look at your fishing macro, most of them have a sort of "destroy trash" set up already. If yours does not, may want to look into another one --shrugs-- though the MQ2Cursor plugin will do the job, it sort of requires you to either have the item in your inventory, or know the item's ID number.