It's kind of a dangerous thing to do. Macro movement, including mq2navigation, is very noticeable to players. The only way I'd ever run such a macro would be if there were constant checks that the zone was empty.
I'm on FV, the zones with collectibles always have someone in them, so there never would be a safe time to make/test one. Or am I missing something? Is there a specific abandoned zone you are looking to pickup ground spawns from?