Using the inis here isn't a bad idea, but if it's your first time using KA, I recommend reading the manual in the link pointed above and doing your own inis. It really doesn't take more than a couple hours. It may seem confusing when you begin using it, but just make sure you take the time to read everything and do at least one ini thoroughly.
At some point, you'll want a particular playstyle for one of your toons, you'll want to change spells and clickies, you might want to try a different toon pulling, etc.; there's tons of stuff you'll change and you want to make sure you are comfortable with manipulating KA. There are no inis that you'll set once and you'll never have to touch again, unless you're 100 with max AAs, all r3 spells and BiS gear. It's my personal opinion, but I think if you try to skip scenes, it'll make it worse and it might even ruin your KA experience to a certain extent. Therefore, I recommend taking your time, it's fairly user-friendly once you give it a shot.
The basics:
MQ2 is the tp tool that you need to launch.
KA is a very well designed macro running via MQ2.
The .ini files are what KA uses to load your characters configurations.
When you run /mac kissassist for the first time on a toon, like eqgeek said, you are basically telling KA that ''Hey, my paladin exists, make a file so that I can make him do what I want''.
Once that file is created, you'll want to configure your toons the way you would like to use them, and then, every time you use KA on a certain toon, it'll load its configs from that file(.ini) that you edited.
Plugins are basically extensions of what MQ2 can do.
To use KA, you will have to enable certain plugins, otherwise many functions won't work the way they are intended. All of these plugins are listed in the KA guide on this website.