You can see my Warrior's hotbars in this thread:
https://www.redguides.com/community/threads/quick-tip-on-setting-up-hotkeys.67005/
How it works is like this:
My Warrior is very automated, I barely need to do anything, so I moved everything that gets automatically used to other pages so that my page 1 is clear for stuff I need to use regularly.
Starting from the bottom row at the left, I have the melee icon because I like lots of indications whether I'm fighting or not. Then I have my 3 main taunts that I use to pull with (if I am pulling manually), and they get used automatically mid combat too. The Stout Defense button is there just so I can see how quick it is getting used automatically. Attack!!! doesnt actually do anything anymore. The rest are MQ2 commands, move to me, all follow me, etc.
The next row up I have a few things that aren't automated. Call of Challenge I could move because that is automated now too... but the ones either side of it I only use manually to push or pull the enemy if I want to reposition it a bit. Rampage and Area Taunt are automated but I like to be able to click them sometimes myself too. The rest of that row doesn't do much.
Almost the entire top 2 rows are just MQ2 commands. Invis group, drop invis, levi group, pacify my target, evac now, coth me, start/stop my warrior's macro, set all group mates to click "never" when looting, etc.
That is mostly it. I have a few other things on page 2 that I use, like my button to have everyone click a door, but this is mostly it.