thanks for all of the responses. So here is the example. And I am a 100% noob at this literally just learned how to do this last night.
I am on my necro, I have a 5 dot macro. I hit the macro and it casts 5 dots in a row without me having to cast them one by one (this is obv to you guys but even this is new to me) - as I am in the middle of casting dots, I hit the "nuke" key on my necro that controls my mage. When I hit that button, it interrupts the casting of the dots my necro is doing. It is the same if I hit the 5 dot macro and then hit a random spell in the middle, it messes up the flow of the dot macro, if that makes sense? And I am still trying to learn kissassist and all of this, i just have me and my mage, but I plan to 6 box when I get the hang of it,