Caveat emptor: This site is not associated with Daybreak Game Company LLC. Use of the free, open-source MacroQuest software, other software found here, and certain strategies may be against their TOS/EULA.
From our experience since 2004, we don't know of a single player banned for simply using MacroQuest, so long as they avoided active-hacks (which we don't support) and were not AFK. We maintain our "Very Vanilla" MacroQuest compile with safety in mind, as we use it for our own accounts we've been playing since '99.
It should also be noted that automating a video game character is not against any law.